GENOTOXIC相关论文
Ultra-Sensitive LC-MS/MS Method for the Trace Level Quantification of Six Potential Genotoxic Nitros
Nitrosamine impurities are potentially genotoxic which are considered under cohort of concern as per ICH M7 guidelines a......
Simultaneous and Trace Level Quantification of Five Potential Genotoxic Impurities in Ranolazine Act
Highly sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed for the simultaneou......
A High Sensitive LC-MS/MS Method for the Simultaneous Determination of Potential Genotoxic Impuritie
A simple, rapid, and highly sensitive LC-MS/MS method has been developed for the simultaneous and trace level quantifica......
A High Sensitive LC-MS/MS Method for the Simultaneous Determination of Potential Genotoxic Impuritie
A simple, rapid, and highly sensitive LC-MS/MS method has been developed for the simultaneous and trace level quantifica......
RecA与UvrA是细胞SOS系统中重要的修复蛋白，在细胞DNA损伤后诱导表达．将报告基因绿色荧光蛋白基因（gfpmut3a）分别置于recA和uvrA启动子......
[目的]应用单细胞凝胶电泳技术评价毛鸡骨草的遗传毒性。[方法]试验分为5组：阳性对照组（环磷酰胺组）、阴性对照组（生理盐水组）、毛鸡骨......
利用彗星实验检测渤海区主要入海河流遗传毒性.以虾虎鱼为受试生物,暂养在河口水样中,染毒48h,取外周血细胞,运用彗星实验检测外周......
目的与方法：应用蚕豆和大蒜根尖细胞微核技术对涑水河闻喜河段污水及其沿岸井水遗传毒物的污染状况进行了检测。结果：蚕豆检测结果表......
Objective: To assess and compare the cytotoxic, genotoxic, apoptotic and reactive oxygen species(ROS) generating effects......
4-hydrazinobenzoic acid has been highlighted as one of the potential genotoxic impurities (PGIs). A sensitive HPLC metho......
4-hydrazinobenzoic acid has been highlighted as one of the potential genotoxic impurities (PGIs). A sensitive HPLC metho......
Defining impurity profile is key element to ensure safe, efficacious and quality human drugs. Impurity profiling changed......
Background: In oral and maxillofacial surgery, synthetic bone grafts are most widely used as bone substitutes, due to th......
报道了在正常营养与营养不足状态下，长期接触不同浓度水氟的人群外周血淋巴细胞姊妹染色单体交换（ＳＣＥ）频率，以评价对人群的遗传性危险度。......
With the ever increasing complexity of active pharmaceutical ingredient (API) preparations, more potential genotoxic imp......
Genotoxicity of Water Extracts from Sewage Effluents in the Kanagawa Prefecture, Japan Using the Nov
The genotoxic activities of effluents from drainage water treatment plants were examined by using the novel <em>umu</em>......
